Studies on cleaning validation for a cream and ointment manufacturing line
نویسندگان
چکیده
منابع مشابه
Development and Validation of RP-HPLC-UV Method for Determination of Diclofenac Sodium Residues on Surfaces for Cleaning Validation
In recent years, cleaning validation has achieved a position of increasing in the pharmaceutical industry. It provides assurance to the cleaning procedure that ensures equipment is consistently cleaned from the product, detergent and microbial residues to an acceptable level to avoid cross-contamination and adulteration of drug product with other active ingredients. The aim of this study was to...
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The manufacturing equipment in pharmaceutical industry, could be used in multiple and sharedproduction lines, therefore there is the possibility for the products components and active ingredients tointermix and pollute one another. In this purpose the cleaning methods are used, to reduce the residueslevels from the machinery surfaces and decrease the residues to acceptable level but these metho...
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Pharmaceutical product and active pharmaceutical ingredients (APIs) can be contaminated by other pharmaceutical products or APIs, by cleaning agents, by microorganisms or by other materials e.g. air borne particle, dust, lubricants, raw materials, intermediates. Mainly cleaning is performed to remove product and non-product contaminating material. Ineffective cleaning can lead to adulterated pr...
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In recent years, as general purpose computers like personal computers spread into control systems in manufacturing fields, the control systems are expected to be integrated with business systems such as quality management systems, cost management systems and ERP(Enterprise Resource Planning) systems. This integration makes it possible to deliver data rapidly between control systems and business...
متن کاملOn-line outlier detection and data cleaning
Outliers are observations that do not follow the statistical distribution of the bulk of the data, and consequently may lead to erroneous results with respect to statistical analysis. Many conventional outlier detection tools are based on the assumption that the data is identically and independently distributed. In this paper, an outlier-resistant data filter-cleaner is proposed. The proposed d...
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ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2016
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v15i11.5